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Fireside chat at Sequoia Ascent 2026 from a ~week ago. Some highlights:

Andrej Karpathy Twitter · Andrej Karpathy (@karpathy) · 2026-04-30

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Topics: llm-new-applicationsai-agentscomputer-use-ai

Claims

  • LLMs enable fundamentally new application categories, not merely acceleration of existing workflows.
  • Karpathy presented three examples of genuinely new LLM horizons at Sequoia Ascent 2026, including 'menugen' — an app category that can be entirely subsumed by AI.

Key quotes

The first theme I tried to push on is that LLMs are about a lot more than just speeding up what existed before (e.g. coding). Three examples of new horizons: 1. menugen: an app that can be fully engulfed by [AI]