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Claude Meets Blackwell Ultra: Anthropic’s Models Now Run on NVIDIA GB300 in Azure

NVIDIA Blog · Dave Salvator · 2026-06-29

Anthropic's Claude models are now generally available on Microsoft Azure's Foundry service running on NVIDIA GB300 Blackwell Ultra GPUs, enabling enterprises to build and deploy autonomous AI agents with high inference performance and reduced total cost of ownership.

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Topics: enterprise-aiai-hardwarecloud-infrastructureagentic-systemsanthropic

Claims

  • Claude models in Microsoft Foundry running on NVIDIA GB300 NVL72 systems with Quantum-X800 InfiniBand networking are now generally available on Azure.
  • NVIDIA is integrating its tools into the Anthropic stack to give Claude agents domain-specific abilities through verified agent skills on NVIDIA accelerated computing.
  • The three-way partnership between Microsoft, NVIDIA, and Anthropic was first announced in November to expand enterprise access to Claude.
  • The NVIDIA Secure Agent Workspace Reference Design provides a blueprint for running autonomous agents in governed environments with infrastructure-level identity, credential, and runtime policy controls.

Key quotes

Enterprises can now build and run more powerful agentic systems, including autonomous and specialized sub-agents that can work across business domains to perform advanced tasks.
Through NVIDIA verified agent skills, enabled by access to NVIDIA accelerated computing, enterprises can embed AI agents deeply into their business and use them as the operating system for the organization.